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HPE ProLiant DL385

AMD EPYC performance and core density in a versatile 2U platform.

Full manufacturer warrantyAuthorized channel48-hour quote

We help you choose, configure, and deliver the right system — no obligation.

HPE ProLiant DL385 — HPE enterprise hardware
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HPE ProLiant DL385 hardware detail 1
HPE ProLiant DL385 hardware detail 2
HPE ProLiant DL385 hardware detail 3

Configuration at a Glance

Form Factor2U rackmount
CPUAMD EPYC (single or dual socket)
MemoryUp to 8TB (generation-dependent)
StorageNVMe / SAS / SATA (configurable)

Tailored per engagement. Full technical overview below.

Configuration Options

Core specifications for this system. Every component is configurable to your workload — request a quote for a tailored build.

Processor

AMD EPYC (single or dual socket)

Memory

Up to 8TB (generation-dependent)

Storage

NVMe / SAS / SATA (configurable)

Overview

The HPE ProLiant DL385 brings AMD EPYC processors to HPE's proven 2U platform, delivering exceptional core counts and memory bandwidth per server. Nexus Compute sources DL385 systems for workloads that benefit from EPYC's density and value — virtualization, analytics, and core-hungry applications.

Who This Solution Is For

Teams running core-dense virtualization or VDI
Analytics and HPC-adjacent workloads
Organizations optimizing per-core licensing economics
IT teams favoring AMD EPYC price-performance

Business Benefits

Exceptional core density

High EPYC core counts host more VMs or threads per server, improving consolidation ratios.

Strong memory bandwidth

EPYC's memory architecture benefits analytics and bandwidth-sensitive workloads.

Licensing efficiency

For some per-socket licensed software, high-core single sockets can reduce license costs.

HPE management and support

EPYC performance with the familiar iLO and OneView ecosystem.

Typical Business Use Cases

1

Core-dense virtualization and VDI

2

Analytics and in-memory workloads

3

Containerized platforms needing high thread counts

4

General compute favoring AMD EPYC value

Industry Applications

Financial ServicesEducation & ResearchSoftware & SaaSHealthcare & Life Sciences

Technical Overview

A 2U platform built on AMD EPYC processors with high core counts, large DDR memory capacity, flexible storage, iLO management, and redundant power.

Form Factor2U rackmount
CPUAMD EPYC (single or dual socket)
MemoryUp to 8TB (generation-dependent)
StorageNVMe / SAS / SATA (configurable)
ManagementHPE iLO + OneView
SecurityAMD Infinity Guard features
PowerRedundant PSUs (N+1)
WarrantyHPE support (configurable)

Specifications are indicative and configured to each engagement. Request a quote for a configuration tailored to your requirements.

Warranty, Support & Fulfillment

Every system ships from an authorized channel, configured and tested, with the documentation enterprise buyers need — backed by warranty and a dedicated account team.

Enterprise Warranty

Full manufacturer warranty with optional on-site, next-business-day support and extended coverage.

Authorized Channel

Sourced through Tier-1 distribution and OEM partners — never grey market. Asset & warranty records included.

Lead Time & Deployment

48-hour quotes, then configured, burn-in tested, and delivered on a committed schedule.

Nationwide Fulfillment

Coordinated logistics, rack-and-stack, and delivery wherever your infrastructure lives.

Frequently Asked Questions

AMD EPYC or Intel Xeon — how do we decide?

EPYC typically wins on core density, memory bandwidth, and per-core value; Xeon can lead on certain single-thread and Intel-specific features. We advise based on your workload and software.

Does EPYC affect software compatibility?

Modern enterprise software runs on EPYC without issue. For specific certified applications we confirm support during the quote.

Can it reduce our licensing costs?

In some per-socket licensing scenarios, high-core single-socket EPYC configurations reduce license counts. We help model this.

Hardware Assistance

Configure the HPE ProLiant DL385 with Nexus Compute

Tell us your requirements and a hardware specialist will help you specify, configure, and quote the right system — typically within two business days. No obligation.