HPE ProLiant DL385
AMD EPYC performance and core density in a versatile 2U platform.
We help you choose, configure, and deliver the right system — no obligation.




Configuration at a Glance
Tailored per engagement. Full technical overview below.
Configuration Options
Core specifications for this system. Every component is configurable to your workload — request a quote for a tailored build.
AMD EPYC (single or dual socket)
Up to 8TB (generation-dependent)
NVMe / SAS / SATA (configurable)
Overview
The HPE ProLiant DL385 brings AMD EPYC processors to HPE's proven 2U platform, delivering exceptional core counts and memory bandwidth per server. Nexus Compute sources DL385 systems for workloads that benefit from EPYC's density and value — virtualization, analytics, and core-hungry applications.
Who This Solution Is For
Business Benefits
Exceptional core density
High EPYC core counts host more VMs or threads per server, improving consolidation ratios.
Strong memory bandwidth
EPYC's memory architecture benefits analytics and bandwidth-sensitive workloads.
Licensing efficiency
For some per-socket licensed software, high-core single sockets can reduce license costs.
HPE management and support
EPYC performance with the familiar iLO and OneView ecosystem.
Typical Business Use Cases
Core-dense virtualization and VDI
Analytics and in-memory workloads
Containerized platforms needing high thread counts
General compute favoring AMD EPYC value
Industry Applications
Technical Overview
A 2U platform built on AMD EPYC processors with high core counts, large DDR memory capacity, flexible storage, iLO management, and redundant power.
| Form Factor | 2U rackmount |
| CPU | AMD EPYC (single or dual socket) |
| Memory | Up to 8TB (generation-dependent) |
| Storage | NVMe / SAS / SATA (configurable) |
| Management | HPE iLO + OneView |
| Security | AMD Infinity Guard features |
| Power | Redundant PSUs (N+1) |
| Warranty | HPE support (configurable) |
Specifications are indicative and configured to each engagement. Request a quote for a configuration tailored to your requirements.
Warranty, Support & Fulfillment
Every system ships from an authorized channel, configured and tested, with the documentation enterprise buyers need — backed by warranty and a dedicated account team.
Enterprise Warranty
Full manufacturer warranty with optional on-site, next-business-day support and extended coverage.
Authorized Channel
Sourced through Tier-1 distribution and OEM partners — never grey market. Asset & warranty records included.
Lead Time & Deployment
48-hour quotes, then configured, burn-in tested, and delivered on a committed schedule.
Nationwide Fulfillment
Coordinated logistics, rack-and-stack, and delivery wherever your infrastructure lives.
Frequently Asked Questions
AMD EPYC or Intel Xeon — how do we decide?
EPYC typically wins on core density, memory bandwidth, and per-core value; Xeon can lead on certain single-thread and Intel-specific features. We advise based on your workload and software.
Does EPYC affect software compatibility?
Modern enterprise software runs on EPYC without issue. For specific certified applications we confirm support during the quote.
Can it reduce our licensing costs?
In some per-socket licensing scenarios, high-core single-socket EPYC configurations reduce license counts. We help model this.
Hardware Assistance
Configure the HPE ProLiant DL385 with Nexus Compute
Tell us your requirements and a hardware specialist will help you specify, configure, and quote the right system — typically within two business days. No obligation.